PIs of General Access proposals can add new samples in the PNCC User Portal. It is expected that all approved proposals utilize the samples they submitted during peer-review initially. Additional samples that align with the overall scientific scope of the original proposal or build upon prior samples may be added.
For example, proposing to extend a current study to a new isoform, homolog, mutant and/or addition of ligand or buffer conditions would be acceptable. However, adding samples from a completely different or biologically unrelated system (e.g., switching from an ion transporter to a ribosome complex) would require a new proposal submission.
Adding samples must be done in the Portal before sending new samples/grids to PNCC. Requested BSL-2 grids undergo additional approval steps for evaluating the required Institutional Biosafety Committee (IBC) document.